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Spontaneous Intracerebral Hemorrhage: A Global Validation of Prognostic Scores Spontaneous intracerebral hemorrhage (ICH) remains the deadliest and most functionally devastating subtype of stroke, accounting for nearly half of all stroke-related disability-adjusted life years worldwide. In acute neurology and neurocritical care units, clinical decision-making relies heavily on risk stratification scores to forecast patient trajectories, allocate intensive …

Benchmarking Clinical Prediction in Intracerebral Hemorrhage Leer más »

Reframing Chronic Metabolic Disease: Dr. Jeffrey I. Mechanick Unveils the Malnutrition-Based Chronic Disease (MBCD) Model in Endocrine Practice Chronic metabolic noncommunicable diseases represent an overwhelming global epidemic: more than 75% of adults in the United States live with at least one chronic condition, over 50% suffer from multimorbidity, and globally more than a third of …

Reframing Chronic Metabolic Disease Leer más »

Early Thrombolysis Unlocks Maximum Benefit Prior to Thrombectomy in Acute Ischemic Stroke In acute ischemic stroke driven by anterior-circulation large-vessel occlusion (LVO), the clinical debate surrounding whether to administer intravenous thrombolysis (IVT) prior to endovascular thrombectomy (EVT) vs. proceeding directly to EVT has centered on real-world effectiveness and time-sensitivity. A landmark multinational study utilizing data …

Early Thrombolysis Unlocks Maximum Benefit Leer más »

Migraine History Linked to Elevated Ischemic Stroke Risk in Postmenopausal Women: WHI Analysis Postmenopausal women with a history of physician-diagnosed migraine face a modestly higher risk of incident ischemic stroke, independent of traditional cardiovascular and sex-specific risk factors, according to a major new analysis of the Women’s Health Initiative (WHI) cohort published in Neurology. The …

Migraine and Ischemic Stroke Leer más »

Transculturalizing Cardiometabolic Care: How Chile is Redefining Type 2 Diabetes Prevention Beyond Glycemic Control SANTIAGO, CHILE — Traditional management models for type 2 diabetes (T2D) are facing a paradigm shift. A landmark consensus paper published by the Mechanick Transculturalization Research and Innovation ConSortium (METRICS)—led by Dr. Ramfis Nieto-Martínez in collaboration with Dr. Goodarz Danaei (Bernard …

Transculturalizing Cardiometabolic Care in Chile Leer más »